Table of Contents

May 24, 2012; 119 (21)

Inside Blood

    • Alexander Zarbock

    PHAGOCYTES & GRANULOCYTES: The shady side of dasatinib

    Blood 2012 119:4817-4818; doi:10.1182/blood-2012-03-418582
    • Peter Möller and
    • Andreas Viardot

    CLINICAL TRIALS: Antibiotics as first-line therapy for Hp-associated gastric large B-cell lymphoma? Probably yes.

    Blood 2012 119:4818-4819; doi:10.1182/blood-2012-03-417345
    • Qi Yang and
    • Avinash Bhandoola

    HEMATOPOIESIS & STEM CELLS: Decoding HSC heterogeneity

    Blood 2012 119:4819-4820; doi:10.1182/blood-2012-03-417238
    • Samuel Strober and
    • Robert Lowsky

    TRANSPLANTATION: Rare cells predict GVHD

    Blood 2012 119:4820-4821; doi:10.1182/blood-2012-04-417311

Blood Work

    • Selay Lam and
    • Cyrus C. Hsia

    Peripheral blood candidiasis

    Blood 2012 119:4822; doi:10.1182/blood-2011-09-378737

Perspectives

    • Karen K. Hirschi

    Hemogenic endothelium during development and beyond

    Blood 2012 119:4823-4827; published ahead of print March 13, 2012, doi:10.1182/blood-2011-12-353466

Review Article

    • Margaret H. Baron,
    • Joan Isern,
    • and Stuart T. Fraser

    The embryonic origins of erythropoiesis in mammals

    Blood 2012 119:4828-4837; published ahead of print February 15, 2012, doi:10.1182/blood-2012-01-153486

Clinical Trials and Observations

    • Sung-Hsin Kuo,
    • Kun-Huei Yeh,
    • Ming-Shiang Wu,
    • Chung-Wu Lin,
    • Ping-Ning Hsu,
    • Hsiu-Po Wang,
    • Li-Tzong Chen,
    • and Ann-Lii Cheng

    CME article Helicobacter pylori eradication therapy is effective in the treatment of early-stage H pylori–positive gastric diffuse large B-cell lymphomas

    Blood 2012 119:4838-4844; published ahead of print March 7, 2012, doi:10.1182/blood-2012-01-404194
    • Jorge J. Castillo,
    • Nikhil Mull,
    • John L. Reagan,
    • Saed Nemr,
    • and Joanna Mitri

    Increased incidence of non-Hodgkin lymphoma, leukemia, and myeloma in patients with diabetes mellitus type 2: a meta-analysis of observational studies

    Blood 2012 119:4845-4850; published ahead of print April 10, 2012, doi:10.1182/blood-2011-06-362830
    • Peter Dreger,
    • Hartmut Döhner,
    • Fabienne McClanahan,
    • Raymonde Busch,
    • Matthias Ritgen,
    • Hildegard Greinix,
    • Anna-Maria Fink,
    • Wolfgang Knauf,
    • Michael Stadler,
    • Michael Pfreundschuh,
    • Ulrich Dührsen,
    • Günter Brittinger,
    • Manfred Hensel,
    • Johannes Schetelig,
    • Dirk Winkler,
    • Andreas Bühler,
    • Michael Kneba,
    • Norbert Schmitz,
    • Michael Hallek,
    • and Stephan Stilgenbauer
    • , on behalf of the German CLL Study Group

    Early autologous stem cell transplantation for chronic lymphocytic leukemia: long-term follow-up of the German CLL Study Group CLL3 trial

    Blood 2012 119:4851-4859; published ahead of print April 5, 2012, doi:10.1182/blood-2011-09-378505
    • Shaji K. Kumar,
    • Suzanne R. Hayman,
    • Francis K. Buadi,
    • Vivek Roy,
    • Martha Q. Lacy,
    • Morie A. Gertz,
    • Jacob Allred,
    • Kristina M. Laumann,
    • Leif P. Bergsagel,
    • David Dingli,
    • Joseph R. Mikhael,
    • Craig B. Reeder,
    • A. Keith Stewart,
    • Steven R. Zeldenrust,
    • Philip R. Greipp,
    • John A. Lust,
    • Rafael Fonseca,
    • Stephen J. Russell,
    • S. Vincent Rajkumar,
    • and Angela Dispenzieri

    Lenalidomide, cyclophosphamide, and dexamethasone (CRd) for light-chain amyloidosis: long-term results from a phase 2 trial

    Blood 2012 119:4860-4867; published ahead of print April 13, 2012, doi:10.1182/blood-2012-01-407791

Hematopoiesis and Stem Cells

    • Huili Lu,
    • Shunying Zhu,
    • Lan Qian,
    • Di Xiang,
    • Wu Zhang,
    • Aifang Nie,
    • Jin Gao,
    • Mingyuan Wu,
    • Jinming Gao,
    • Bao Lu,
    • Yan Yu,
    • Wei Han,
    • and Anja Moldenhauer

    Activated expression of the chemokine Mig after chemotherapy contributes to chemotherapy-induced bone marrow suppression and lethal toxicity

    Blood 2012 119:4868-4877; published ahead of print April 3, 2012, doi:10.1182/blood-2011-07-367581
    • Rositsa I. Koleva,
    • Scott B. Ficarro,
    • Hanna S. Radomska,
    • Marlene J. Carrasco-Alfonso,
    • John A. Alberta,
    • James T. Webber,
    • C. John Luckey,
    • Guido Marcucci,
    • Daniel G. Tenen,
    • and Jarrod A. Marto

    C/EBPα and DEK coordinately regulate myeloid differentiation

    Blood 2012 119:4878-4888; published ahead of print April 3, 2012, doi:10.1182/blood-2011-10-383083
    • Tomoyuki Shimazu,
    • Ryuji Iida,
    • Qingzhao Zhang,
    • Robert S. Welner,
    • Kay L. Medina,
    • José Alberola-lla,
    • and Paul W. Kincade

    CD86 is expressed on murine hematopoietic stem cells and denotes lymphopoietic potential

    Blood 2012 119:4889-4897; published ahead of print February 27, 2012, doi:10.1182/blood-2011-10-388736
    • Nan Xiao,
    • Kaushal Jani,
    • Kelly Morgan,
    • Rachel Okabe,
    • Dana E. Cullen,
    • Jonathan L. Jesneck,
    • and Glen D. Raffel

    Hematopoietic stem cells lacking Ott1 display aspects associated with aging and are unable to maintain quiescence during proliferative stress

    Blood 2012 119:4898-4907; published ahead of print April 6, 2012, doi:10.1182/blood-2012-01-403089

Immunobiology

    • Kenjiro Tadagaki,
    • Daniela Tudor,
    • Florence Gbahou,
    • Pia Tschische,
    • Maria Waldhoer,
    • Morgane Bomsel,
    • Ralf Jockers,
    • and Maud Kamal

    Human cytomegalovirus-encoded UL33 and UL78 heteromerize with host CCR5 and CXCR4 impairing their HIV coreceptor activity

    Blood 2012 119:4908-4918; published ahead of print April 10, 2012, doi:10.1182/blood-2011-08-372516
    • Jun Diao,
    • Anastassia Mikhailova,
    • Michael Tang,
    • Hongtao Gu,
    • Jun Zhao,
    • and Mark S. Cattral

    Immunostimulatory conventional dendritic cells evolve into regulatory macrophage-like cells

    Blood 2012 119:4919-4927; published ahead of print April 6, 2012, doi:10.1182/blood-2011-11-392894
    • Patricia Ribeiro-dos-Santos,
    • Emma L. Turnbull,
    • Marta Monteiro,
    • Agnès Legrand,
    • Karen Conrod,
    • Joshua Baalwa,
    • Pierre Pellegrino,
    • George M. Shaw,
    • Ian Williams,
    • Persephone Borrow,
    • and Benedita Rocha

    Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors

    Blood 2012 119:4928-4938; published ahead of print April 6, 2012, doi:10.1182/blood-2011-12-395186

Lymphoid Neoplasia

    • Sung-Hsin Kuo,
    • Kun-Huei Yeh,
    • Ming-Shiang Wu,
    • Chung-Wu Lin,
    • Ping-Ning Hsu,
    • Hsiu-Po Wang,
    • Li-Tzong Chen,
    • and Ann-Lii Cheng

    CME article Helicobacter pylori eradication therapy is effective in the treatment of early-stage H pylori–positive gastric diffuse large B-cell lymphomas

    Blood 2012 119:4838-4844; published ahead of print March 7, 2012, doi:10.1182/blood-2012-01-404194
    • Peter Dreger,
    • Hartmut Döhner,
    • Fabienne McClanahan,
    • Raymonde Busch,
    • Matthias Ritgen,
    • Hildegard Greinix,
    • Anna-Maria Fink,
    • Wolfgang Knauf,
    • Michael Stadler,
    • Michael Pfreundschuh,
    • Ulrich Dührsen,
    • Günter Brittinger,
    • Manfred Hensel,
    • Johannes Schetelig,
    • Dirk Winkler,
    • Andreas Bühler,
    • Michael Kneba,
    • Norbert Schmitz,
    • Michael Hallek,
    • and Stephan Stilgenbauer
    • , on behalf of the German CLL Study Group

    Early autologous stem cell transplantation for chronic lymphocytic leukemia: long-term follow-up of the German CLL Study Group CLL3 trial

    Blood 2012 119:4851-4859; published ahead of print April 5, 2012, doi:10.1182/blood-2011-09-378505
    • Shaji K. Kumar,
    • Suzanne R. Hayman,
    • Francis K. Buadi,
    • Vivek Roy,
    • Martha Q. Lacy,
    • Morie A. Gertz,
    • Jacob Allred,
    • Kristina M. Laumann,
    • Leif P. Bergsagel,
    • David Dingli,
    • Joseph R. Mikhael,
    • Craig B. Reeder,
    • A. Keith Stewart,
    • Steven R. Zeldenrust,
    • Philip R. Greipp,
    • John A. Lust,
    • Rafael Fonseca,
    • Stephen J. Russell,
    • S. Vincent Rajkumar,
    • and Angela Dispenzieri

    Lenalidomide, cyclophosphamide, and dexamethasone (CRd) for light-chain amyloidosis: long-term results from a phase 2 trial

    Blood 2012 119:4860-4867; published ahead of print April 13, 2012, doi:10.1182/blood-2012-01-407791
    • Javeed Iqbal,
    • Yulei Shen,
    • Yanyan Liu,
    • Kai Fu,
    • Elaine S. Jaffe,
    • Cuiling Liu,
    • Zhongfeng Liu,
    • Cynthia M. Lachel,
    • Karen Deffenbacher,
    • Timothy C. Greiner,
    • Julie M. Vose,
    • Sharathkumar Bhagavathi,
    • Louis M. Staudt,
    • Lisa Rimsza,
    • Andreas Rosenwald,
    • German Ott,
    • Jan Delabie,
    • Elias Campo,
    • Rita M. Braziel,
    • James R. Cook,
    • Raymond R. Tubbs,
    • Randy D. Gascoyne,
    • James O. Armitage,
    • Dennis D. Weisenburger,
    • Timothy W. McKeithan,
    • and Wing C. Chan

    Genome-wide miRNA profiling of mantle cell lymphoma reveals a distinct subgroup with poor prognosis

    Blood 2012 119:4939-4948; published ahead of print April 5, 2012, doi:10.1182/blood-2011-07-370122
    • David W. Scott,
    • Karen L. Mungall,
    • Susana Ben-Neriah,
    • Sanja Rogic,
    • Ryan D. Morin,
    • Graham W. Slack,
    • King L. Tan,
    • Fong Chun Chan,
    • Raymond S. Lim,
    • Joseph M. Connors,
    • Marco A. Marra,
    • Andrew J. Mungall,
    • Christian Steidl,
    • and Randy D. Gascoyne

    Brief report TBL1XR1/TP63: a novel recurrent gene fusion in B-cell non-Hodgkin lymphoma

    Blood 2012 119:4949-4952; published ahead of print April 11, 2012, doi:10.1182/blood-2012-02-414441
    • Yiming Zhou,
    • Qing Zhang,
    • Owen Stephens,
    • Christoph J. Heuck,
    • Erming Tian,
    • Jeffrey R. Sawyer,
    • Marie-Astrid Cartron-Mizeracki,
    • Pingping Qu,
    • Jason Keller,
    • Joshua Epstein,
    • Bart Barlogie,
    • and John D. Shaughnessy, Jr

    e-Blood Prediction of cytogenetic abnormalities with gene expression profiles

    Blood 2012 119:e148-e150; published ahead of print April 10, 2012, doi:10.1182/blood-2011-10-388702

Myeloid Neoplasia

    • Wei-Jong Shia,
    • Akiko J. Okumura,
    • Ming Yan,
    • Ali Sarkeshik,
    • Miao-Chia Lo,
    • Shinobu Matsuura,
    • Yukiko Komeno,
    • Xinyang Zhao,
    • Stephen D. Nimer,
    • John R. Yates III,
    • and Dong-Er Zhang

    PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potential

    Blood 2012 119:4953-4962; published ahead of print April 12, 2012, doi:10.1182/blood-2011-04-347476
    • Elena A. Federzoni,
    • Peter J. M. Valk,
    • Bruce E. Torbett,
    • Torsten Haferlach,
    • Bob Löwenberg,
    • Martin F. Fey,
    • and Mario P. Tschan

    PU.1 is linking the glycolytic enzyme HK3 in neutrophil differentiation and survival of APL cells

    Blood 2012 119:4963-4970; published ahead of print April 12, 2012, doi:10.1182/blood-2011-09-378117
    • Ye Chen,
    • Rodrigo Jacamo,
    • Yue-xi Shi,
    • Rui-yu Wang,
    • Venkata Lokesh Battula,
    • Sergej Konoplev,
    • Dirk Strunk,
    • Nicole A. Hofmann,
    • Andreas Reinisch,
    • Marina Konopleva,
    • and Michael Andreeff

    Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment

    Blood 2012 119:4971-4980; published ahead of print April 5, 2012, doi:10.1182/blood-2011-11-389957
    • Xiao-Shuang Wang,
    • Jia-Nan Gong,
    • Jia Yu,
    • Fang Wang,
    • Xin-Hua Zhang,
    • Xiao-Lin Yin,
    • Zhen-Qing Tan,
    • Zi-Mian Luo,
    • Gui-Hua Yang,
    • Chao Shen,
    • and Jun-Wu Zhang

    MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia

    Blood 2012 119:4992-5004; published ahead of print April 4, 2012, doi:10.1182/blood-2011-10-385716

Phagocytes, Granulocytes, and Myelopoiesis

    • Rositsa I. Koleva,
    • Scott B. Ficarro,
    • Hanna S. Radomska,
    • Marlene J. Carrasco-Alfonso,
    • John A. Alberta,
    • James T. Webber,
    • C. John Luckey,
    • Guido Marcucci,
    • Daniel G. Tenen,
    • and Jarrod A. Marto

    C/EBPα and DEK coordinately regulate myeloid differentiation

    Blood 2012 119:4878-4888; published ahead of print April 3, 2012, doi:10.1182/blood-2011-10-383083
    • Elena A. Federzoni,
    • Peter J. M. Valk,
    • Bruce E. Torbett,
    • Torsten Haferlach,
    • Bob Löwenberg,
    • Martin F. Fey,
    • and Mario P. Tschan

    PU.1 is linking the glycolytic enzyme HK3 in neutrophil differentiation and survival of APL cells

    Blood 2012 119:4963-4970; published ahead of print April 12, 2012, doi:10.1182/blood-2011-09-378117
    • Krisztina Futosi,
    • Tamás Németh,
    • Robert Pick,
    • Tibor Vántus,
    • Barbara Walzog,
    • and Attila Mócsai

    Dasatinib inhibits proinflammatory functions of mature human neutrophils

    Blood 2012 119:4981-4991; published ahead of print March 12, 2012, doi:10.1182/blood-2011-07-369041
    • Xiao-Shuang Wang,
    • Jia-Nan Gong,
    • Jia Yu,
    • Fang Wang,
    • Xin-Hua Zhang,
    • Xiao-Lin Yin,
    • Zhen-Qing Tan,
    • Zi-Mian Luo,
    • Gui-Hua Yang,
    • Chao Shen,
    • and Jun-Wu Zhang

    MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia

    Blood 2012 119:4992-5004; published ahead of print April 4, 2012, doi:10.1182/blood-2011-10-385716
    • Joanna Fares,
    • Richard Koller,
    • Rita Humeniuk,
    • Linda Wolff,
    • and Juraj Bies

    The tumor suppressor p15Ink4b regulates the differentiation and maturation of conventional dendritic cells

    Blood 2012 119:5005-5015; published ahead of print March 28, 2012, doi:10.1182/blood-2011-10-387613

Platelets and Thrombopoiesis

    • Jon E. Arnason,
    • Federico Campigotto,
    • Donna Neuberg,
    • and James B. Bussel

    Abnormalities in IgA and IgM are associated with treatment-resistant ITP

    Blood 2012 119:5016-5020; published ahead of print April 6, 2012, doi:10.1182/blood-2011-09-381020

Red Cells, Iron, and Erythropoiesis

    • Antonella Nai,
    • Alessia Pagani,
    • Giacomo Mandelli,
    • Maria Rosa Lidonnici,
    • Laura Silvestri,
    • Giuliana Ferrari,
    • and Clara Camaschella

    Deletion of TMPRSS6 attenuates the phenotype in a mouse model of β-thalassemia

    Blood 2012 119:5021-5029; published ahead of print April 6, 2012, doi:10.1182/blood-2012-01-401885

Transplantation

    • Peter Dreger,
    • Hartmut Döhner,
    • Fabienne McClanahan,
    • Raymonde Busch,
    • Matthias Ritgen,
    • Hildegard Greinix,
    • Anna-Maria Fink,
    • Wolfgang Knauf,
    • Michael Stadler,
    • Michael Pfreundschuh,
    • Ulrich Dührsen,
    • Günter Brittinger,
    • Manfred Hensel,
    • Johannes Schetelig,
    • Dirk Winkler,
    • Andreas Bühler,
    • Michael Kneba,
    • Norbert Schmitz,
    • Michael Hallek,
    • and Stephan Stilgenbauer
    • , on behalf of the German CLL Study Group

    Early autologous stem cell transplantation for chronic lymphocytic leukemia: long-term follow-up of the German CLL Study Group CLL3 trial

    Blood 2012 119:4851-4859; published ahead of print April 5, 2012, doi:10.1182/blood-2011-09-378505
    • Aristeidis Chaidos,
    • Scott Patterson,
    • Richard Szydlo,
    • Mohammed Suhail Chaudhry,
    • Francesco Dazzi,
    • Edward Kanfer,
    • Donald McDonald,
    • David Marin,
    • Dragana Milojkovic,
    • Jiri Pavlu,
    • John Davis,
    • Amin Rahemtulla,
    • Katy Rezvani,
    • John Goldman,
    • Irene Roberts,
    • Jane Apperley,
    • and Anastasios Karadimitris

    Graft invariant natural killer T-cell dose predicts risk of acute graft-versus-host disease in allogeneic hematopoietic stem cell transplantation

    Blood 2012 119:5030-5036; published ahead of print February 27, 2012, doi:10.1182/blood-2011-11-389304

Vascular Biology

    • Yucheng Yao,
    • Medet Jumabay,
    • Albert Ly,
    • Melina Radparvar,
    • Anthony H. Wang,
    • Raushan Abdmaulen,
    • and Kristina I. Boström

    Crossveinless 2 regulates bone morphogenetic protein 9 in human and mouse vascular endothelium

    Blood 2012 119:5037-5047; published ahead of print April 3, 2012, doi:10.1182/blood-2011-10-385906
    • Benoit Detry,
    • Charlotte Erpicum,
    • Jenny Paupert,
    • Silvia Blacher,
    • Catherine Maillard,
    • Françoise Bruyère,
    • Hélène Pendeville,
    • Thibault Remacle,
    • Vincent Lambert,
    • Cédric Balsat,
    • Sandra Ormenese,
    • Françoise Lamaye,
    • Els Janssens,
    • Lieve Moons,
    • Didier Cataldo,
    • Frédéric Kridelka,
    • Peter Carmeliet,
    • Marc Thiry,
    • Jean-Michel Foidart,
    • Ingrid Struman,
    • and Agnès Noel

    Matrix metalloproteinase-2 governs lymphatic vessel formation as an interstitial collagenase

    Blood 2012 119:5048-5056; published ahead of print April 6, 2012, doi:10.1182/blood-2011-12-400267

Other Departments

  • Continuing Medical Education (CME) questions: Helicobacter pylori eradication therapy in gastric DLBCL

    Blood 2012 119:5057; doi:10.1182/blood-2012-05-427690

This Issue

May 24, 2012; 119 (21)
Cover
  1. Inside Blood
  2. Blood Work
  3. Perspectives
  4. Review Article
  5. Clinical Trials and Observations
  6. Hematopoiesis and Stem Cells
  7. Immunobiology
  8. Lymphoid Neoplasia
  9. Myeloid Neoplasia
  10. Phagocytes, Granulocytes, and Myelopoiesis
  11. Platelets and Thrombopoiesis
  12. Red Cells, Iron, and Erythropoiesis
  13. Transplantation
  14. Vascular Biology
  15. Other Departments

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